Hongbo Hu's Lab
The State Key Laboratory of Biotherapy Si-Chuan University
 
Introduction

Huiyuan Zhang, Ph.D.

Professor in Immunology

The State Key Laboratory of Biotherapy

Sichuan University


Education:

2000-2005 Ph.D. of Immunology, Peking Union Medical College. Beijing.


Postdoctoral training:

2007-2012 Department of Immunology, UT MD Anderson Cancer Center Houston, TX.


Working experience:

2012-2016 Instructor, Department of Immunology, UT MD Anderson Cancer Center Houston, TX.

2016-recent Professior, The State Key Laboratory of Biotherapy, Sichuan University

                      Professior, Department of Rheumatology and Immunology, West China Hospital, Sichuan University


Honors and awards:

1995-2000 Excellent undergraduate scholarship, Beijing University of Chinese Medicine

2004-2005 Excellent graduate student scholarship, PUMC&CAMS

2010 Poster presentation winners of Immunology Program Retreat, MD Anderson Cancer Center

2013 Presentation Award of Cancer and Inflammation Center Retreat, MD Anderson Cancer Center


Publication:

1.      Zhang H, Li HS, Hillmer EJ, Zhao Y, Chrisikos TT, Hu H, Wu X, Thompson EJ, Clise-Dwyer K, Millerchip KA, Wei Y, Puebla-Osorio N, Kaushik S, Santos MA, Wang B, Garcia-Manero G, Wang J, Sun SC, Watowich SS. Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 anti-inflammatory activity in hematopoiesis.Proc Natl Acad Sci U S A,2018,doi: 10.1073/pnas.1713889115

2.      Caetano MS, Zhang H, Cumpian AM, Gong L, Unver N, Osrin EJ, Daliri S, Chang SH, Ochoa CE, Hanash SM, Behrens C, Wistuba II, Sternberg C, Kadara H, Ferreira CG, Watowich SS, Moghaddam SJ. IL-6 blockade reprograms the lung tumor microenvironment to limit the development and progression of K-ras mutant lung cancer. Cancer Research,2016;76(11):3189-99.

3.      Hillmer EJ, Zhang H#, Li HS and Watowich SS. STAT3 signaling in immunity. Cytokine Growth Factor Rev, 2016, DOI: 10.1016/j.cytogfr.2016.05.001

4.      Zhang H, Hu H, Greeley N, Jin J, Matthews AJ, Ohashi E, Caetano MS, Li HS, Wu X, Mandal PK, McMurray JS, Moghaddam SJ, Sun SC, Watowich SS. STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13. Nat Commun, 2014, 5:5798.

5.      Yang XO, Zhang H, Kim BS, Niu X, Peng J, Chen Y, Kerketta R, Lee YH, Chang SH, Corry DB, Wang D, Watowich SS, Dong C. The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. Nat Immunol, 2013,14: 732-40.